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Beitragstitel Prostaglandin (Travoprost) - induced cystoid macular edema after complicated cataract surgery – A case report
Autor:innen
  1. Ilan Barchichat Luzerner Kantonsspital Präsentierende:r
  2. Jeremy Howell Luzerner Kantonsspital - Augenklinik
  3. Michael A. Thiel Luzerner Kantonsspital
Präsentationsform ePoster
Themengebiete
  • Uveitis / Intraocular Inflammation
Abstract-Text Background
Topical prostaglandin (PG) analogues are widely used in the medical management of glaucoma for IOP lowering and have a highly favorably safety profile. There is a reported association between PG-analogues and cystoid macular edema (CME) in patients after uneventful phacoemulsification with IOL implantation. PG may lead to disruption of blood-retinal barrier and increase of foveal thickness which is more probable to occur in patients with broken posterior capsule.

History and clinical presentation
A 74 year old woman underwent phacoemulsification with rupture of the posterior capsule, posterior dislocation of lens material. Vitrectomy and 4 months later implantation of a iris-fixated IOL were performed. 5 years later her treating physician discovered a CME (Fig.1) while the patient was asymptomatic. BCVA was 0,32 in the affected eye. The patient was using Travoprost because of a newly diagnosed POWG a few months ago.

Therapy and Outcome
After switching the IOP lowering drug from Travoprost to a combination of Timolol/Dorzolamide BCVA improved to 0.4 and we found after 5 weeks a complete remission of the CME (Fig.3) without any need for antiinflammatory substances.

Conclusions
Caution might be advised when using PG analogues in eyes with risk factors for development of CME. The edema resolves upon cessation of Prostaglandin therapy.