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Beitragstitel Intraocular pressure elevation in keratoconus with coexisting pseudoexfoliation glaucoma; how important is the method of measurement?
Autor:innen
  1. Olga Maria Zabek Department of Ophthalmology, University Hospital Basel, Basel, Switzerland Präsentierende:r
  2. Georgios Panos Whipps Cross University Hospital, Barts Health NHS Trust Präsentierende:r
  3. Despoina Sagri Augenzentrum Zurich
  4. Konstantin Gugleta Universitätsspital Basel
  5. Hendrik Scholl Universitätsspital Basel und Universität Basel
  6. Zisis Gkatzioufas Universitätsspital Basel
Präsentationsform ePoster
Themengebiete
  • External Disease / Cornea
  • Glaucoma
Abstract-Text Purpose: In this report we investigated the association between the intraocular pressure (IOP) values by two different measurement methods and the corneal biomechanical properties in a patient with keratoconus and secondary glaucoma due to pseudoexfoliation syndrome, who developed a marked elevation of intraocular pressure in the right eye.

Methods: IOP was measured over a period of three days with Goldmann applanation tonometry (GAT) and Pascal tonometry (PT). Corneal hysteresis (CH) and corneal resistance factor (CRF) were estimated with the aid of Ocular Response Analyzer (ORA).

Results: CH and CRF were significantly reduced in the right eye compared to the left eye throughout the period of observation (Mann Whitney test, p= 0.011). The difference between both methods of IOP measurement in the right eye, even after IOP correction according to the corneal thickness in GAT, was statistically significant for IOP < 30 mm Hg by GAT (Mann Whitney test, p= 0.023). For IOP values > 30 mm Hg by GAT there was no statistically significant difference between PT and GAT (Mann Whitney test, p= 0.615).


Conclusion: This observation supports the clinical hypothesis that significant decrease in corneal hysteresis (CH) translates in decreased correlation of CH and IOP recordings by GAT and furthermore suggests that after a critical point of CH reduction, the impact of CH on GAT may be comparable of that on PT.